Electronic prescribing is no longer a future ambition, it’s here and it’s changing the way clinicians work. CLEO EPS is an accredited, instant electronic prescribing solution designed to make prescribing faster, safer, and more sustainable. By eliminating paper prescriptions, CLEO EPS delivers significant efficiency gains while supporting the NHS drive for digitisation.
Now fully live and available across secondary care outpatient services, community pharmacy, and independent healthcare providers, CLEO EPS is helping clinicians focus on what matters most: patients, not paperwork.
Why CLEO EPS?
In today’s fast-paced clinical environments, time and resources are precious. CLEO EPS simplifies prescribing with secure, seamless transfer of patient data. Prescriptions can be entered and sent electronically to the patient’s nominated community pharmacy – quickly, safely, and without the risk of lost or illegible paperwork.
Built using cutting-edge FHIR messaging standards and integrated with the NHS Spine, CLEO EPS enables instant prescribing with minimal training. Clinicians can get started after watching a five-minute instruction video.
Real-world impact
CLEO EPS is already making a measurable difference. Following a successful First of Type deployment where CLEO Systems worked collaboratively with Midlands Partnership Foundation Trust and NHS Digital to achieve full NHS accreditation. Today, the solution is supporting clinicians and patients across nearly 30 NHS Trusts, modernising prescribing processes and aligning with NHS England’s digital agenda.
One standout example is Hampshire and Isle of Wight Healthcare NHS Foundation Trust (HIOWH), which deployed CLEO EPS across approximately 60 community teams, including Urgent Treatment Centres, Older People’s Mental Health, CAMHS, Perinatal Services, Specialist Palliative Care, Frailty, and Eating Disorders.
The results speak for themselves:
- 88% of prescribers in scope are actively using CLEO EPS
- Nearly 20,000 prescriptions processed electronically
- Significant time savings—clinicians report up to seven minutes saved per patient
Feedback has been overwhelmingly positive:
“A million times quicker and easier than paper prescriptions. No lost prescriptions, no lost paper trail.”
“It’s a game changer! It has freed up my time and that’s priceless.”
Key benefits delivered
- Improved clinical safety
Eliminates lost or stolen FP10s and issues with illegible handwriting. - Flexible prescribing
Supports emergency prescribing, including evenings and weekends. - Enhanced efficiency
Prescriptions sent at the touch of a button, reducing admin and patient wait times. - Patient convenience
No need to travel to hospital – medication can be collected from the patient’s chosen pharmacy. - Cost savings
Cuts stationery, postage, storage, and mileage costs associated with paper prescriptions. - FHIR messaging compliant
Ensures interoperability, prescription traceability, and robust governance. - Advanced safety features
Search functionality reduces identification errors; full reporting and audit capabilities support compliance. - Sustainability
Reduces paper waste and clinician travel, supporting a greener NHS.

Driving better patient care
By streamlining workflows and reducing administrative burdens, CLEO EPS enables clinicians to dedicate more time to direct patient care. This means more personalised appointments, improved patient satisfaction, and better outcomes.
Clinicians describe CLEO EPS as “revolutionary,” reducing prescription turnaround from hours to minutes. Patients appreciate the convenience and cost savings, while pharmacies report smooth integration and positive feedback.
Future-proofing healthcare
CLEO EPS is more than a prescribing tool – it’s a scalable, innovative solution designed to meet evolving healthcare demands. It benefits clinical teams, improves patient pathways, and supports environmental sustainability.
As David Brown, Managing Director at CLEO Systems, explains:
“CLEO EPS is delivering measurable benefits for clinicians, patients, and the NHS. It supports the national drive for digitisation and electronic prescribing, improving efficiency and enhancing the patient pathway.”
CLEO EPS is not just transforming prescribing – it’s simplifying connected care.



